ALDA develops FluoFab technology from start to finish, from selecting the most opportune Fab and fluorophore couple for the target of interest to setting up scene-specific analytical protocol, through specific functionalization reactions and purification stages.
Many FluoFabs have been created. More others have to come. ..
Protein-protein interaction is a phenomenon associated with almost all biological processes such as transcription and translation, cell-cell adhesion and communication, protein synthesis and degradation, protein control cell cycle and signaling cascades.
PPIs can therefore be used to monitor almost all physiological and pathological processes. ..
ALDA assays are meant to target and monitor protein-protein interactions responsible for crucial physio-pathological events. Associated with clinical data, our assays support both diagnostic and prognostic intents, as well as they can be suitable tools for companion diagnostic in pharmaceutical treatments.
To date, ALDA offers a range of standardized cell-based, paraffin embedded tissues (FFPE) and blood FRET assays that can be tailored to your specific requirements. Nonetheless, we are enthusiastic to provide a complete assay development service. ..
CEINGE- Advanced Biotechnologies in Naples is a non-profit Consortium operating in the field of molecular biology and advanced biotechnology applied to Human Health. It is an excellence in Italy and abroad for the Research and Diagnostics of genetic diseases (hereditary and acquired).
The EuroBioImaging facility in Naples is the Italian Italian Advanced Light Microscopy Node of the European infrastructure ‘Euro-BioImaging’ (EUBI), along with four others imaging facilities located in Genoa, Padua, Florence and Milan. Together the Node sites provide access to a wide range of cutting-edge technologies as well as to a complete service package, from sample preparation to final image analysis, quantitation and visualization.
FLUOFAB can be easily used in all the research lab and can be designed and produced according to the customers desired applications. The conjugation technology used for the generation of the FLUOFAB can also be applied to full length primary antibodies
ALDA bioassays offer the possibility to detect protein-protein interactions that are considered biomarkers for many pathologies directly in patient’s tissues and blood. ALDA bioassays are versatile and can be customized according to the biological matrix analysed and/or the target of interest for the analysis
ALDA bioassays can operate as essential tool for the evaluation of the efficacy of new therapeutic treatments.
Fondo europeo di sviluppo regionale
KIT PER LA MISURA DI INTERAZIONI PROTEINA-PROTEINA COME BIOMARCATORI DI FENOMENI PATOLOGICI
Il progetto ha l’obiettivo della validazione e successivamente la commercializzazione in ambito clinico della tecnologia sviluppata per l’identificazione di interazioni proteina-proteina coinvolte in diverse patologie oncologiche e infiammatorie. La tecnologia e le metodiche proposte sono basate sull’uso di sonde fluorescenti innovative, ottenute tramite metodi originali sviluppati e brevettati dalla società. Il servizio troverà applicazioni su richiesta sia in ambito di ricerca in biologia cellulare e molecolare che in ambito diagnostico nel contesto dello studio di patologie infiammatorie.
Il progetto è cofinanziato dall’Unione Europea, dallo Stato Italiano e dalla Regione Campania, nell’ambito del POR Campania FESR 2014-2020” nell’ambito dell’Avviso Pubblico “Campania Start up 2020”. CUP B61B19001130007